SITAMAQUINE TOSYLATE

Code: SML1542-25MG D2-231

Biochem/physiol Actions

Sitamaquine is an orally active 8-aminoquinoline analog that exhibit antiplasmodial and antileishmanial activities. Sitamaquine accumulates in Leishma...


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€589.10 25MG
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Biochem/physiol Actions

Sitamaquine is an orally active 8-aminoquinoline analog that exhibit antiplasmodial and antileishmanial activities. Sitamaquine accumulates in Leishmania parasites. Sitamaquine potently inhibits respiratory chain complex II (succinate dehydrogenase), which leads to an apoptosis-like death of Leishmania parasites.

Sitamaquine is also known as WR-6026. It is used in the treatment of visceral leishmaniasis.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyLOBPWLFCZDGYKW-UHFFFAOYSA-N
InChI1S/C21H33N3O.C7H8O3S/c1-5-24(6-2)14-10-8-7-9-12-22-20-16-18(25-4)15-19-17(3)11-13-23-21(19)20;1-6-2-4-7(5-3-6)11(8,9)10/h11,13,15-16,22H,5-10,12,14H2,1-4H3;2-5H,1H3,(H,8,9,10)
Quality Level100
SMILES stringCC1=C(C=C(OC)C=C2NCCCCCCN(CC)CC)C2=NC=C1.CC3=CC=C(S(=O)(O)=O)C=C3
solubilityH2O: 15 mg/mL, clear
storage temp.2-8°C
Cas Number1019640-33-5
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